01 / 04

Vitamin D3

(as cholecalciferol)

Supports normal bone health, muscle function and immune function.*

Role

Vitamin D source.

Why this form

Cholecalciferol raises blood vitamin D more effectively than D2; a moderate dose (125% of the daily value) suits supervised use.

When

With the main meal; vitamin D is fat-soluble.

ResearchComparison of vitamin D2 and vitamin D3 supplementation in raising serum 25-hydroxyvitamin D status: a systematic review and meta-analysis.

02 / 04

Vitamin B6

(as pyridoxal-5-phosphate)

Supports normal homocysteine and amino acid metabolism.*

Role

Active B6 cofactor.

Why this form

P-5-P is the active coenzyme form, needing no conversion. 2 mg is 118% of the daily value, well below the 12 mg a day total to stay under from all products.

When

With the main meal.

ResearchThe Role of Vitamin B6 in Peripheral Neuropathy: A Systematic Review.

03 / 04

Folate

(as L-5-methyltetrahydrofolate)

Supports normal homocysteine metabolism and red blood cell formation.*

Role

Active folate for methylation.

Why this form

L-5-MTHF is the active methylated form and does not depend on the MTHFR conversion step. 400 mcg DFE is 100% of the daily value.

When

With the main meal.

ResearchFolate, folic acid and 5-methyltetrahydrofolate are not the same thing.

04 / 04

N-Acetyl Cysteine

Supports the body's own antioxidant (glutathione) production.*

Role

Glutathione precursor.

Why this form

The acetylated form of cysteine is stable and well studied at 600 mg doses.

When

With the main meal.

ResearchExisting and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits.